Rights offer finalisation announcement and distribution of rights offer circular Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) RIGHTS OFFER FINALISATION ANNOUNCEMENT AND DISTRIBUTION OF RIGHTS OFFER CIRCULAR 1. FINALISATION ANNOUNCEMENT Shareholders of Ascendis (“Shareholders”) are referred to the announcement released on SENS on 26 July 2022 wherein Shareholders advised that the board of directors of Ascendis has resolved to raise an amount of R101 530 000 by way of a fully underwritten non-renounceable rights offer (the “Rights Offer”), through an offer of 143 000 000 new Ascendis shares at an issue price of 71 cents per share, in the ratio of 29.70633 Rights Offer Shares for every 100 Ascendis Shares held on the record date for participating in such Rights Offer. Shareholders are also referred to the declaration announcement, release on SENS on 1 August 2022 (the “Declaration Announcement”), setting out the salient dates and times for the Rights Offer. Shareholders are advised that Rights Offer is unconditional. There have been no changes to the salient dates and times for the Rights Offer, as detailed in the Declaration Announcement. Accordingly, the Rights Offer will be implemented in accordance with the salient dates and times set out in the Declaration Announcement. 2. DISTRIBUTION OF CIRCULAR A circular containing full details of the terms of the Rights Offer and a form of instruction in respect of letters of allocation (the “Circular”) will be made available on Ascendis’ website (https://ascendishealth.com/investor- relations/circulars/) on Friday, 5 August 2022. The Circular will be distributed to certificated shareholders on Thursday, 11 August 2022. The Circular will be distributed to dematerialised shareholders on Monday, 15 August 2022. 3 August 2022 Bryanston Sponsor: Questco Proprietary Limited Date: 03-08-2022 11:00:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.