Results of the Annual General Meeting and change to the Board of Directors Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis Health” or “the Company”) RESULTS OF THE ANNUAL GENERAL MEETING AND CHANGE TO THE BOARD OF DIRECTORS Results of the AGM Shareholders are hereby advised that the annual general meeting of the Company was held at 10:00 today, 30 November 2022, via electronic communication (“AGM”). Shareholders are further advised that at the AGM all of the resolutions were passed by the requisite majorities of the Company’s shareholders, save for Ordinary resolution number 2, Special resolution number 2 and Special resolution number 3, which were not passed by the requisite majorities of the Company’s shareholders. Details of the results of the voting at the AGM are as follows: Resolutions Shares Shares Votes for Votes Shares proposed at the AGM voted at voted (%) 1 resolution against abstained General (%) 2 resolution (%)1 Meeting (%) 2 (number) Ordinary resolution 379 846 004 60.84% 77.20% 22.80% 0.33% number 1: Re- appointment of auditors Ordinary resolution 316 881 217 50.75% 20.16% 79.84% 10.42% number 2: Re-election of retiring non- executive director, Harry Smit Ordinary resolution 379 446 004 60.77% 80.01% 19.99% 0.40% number 3: Re-election of retiring non- executive director, Karsten Wellner Ordinary resolution 379 416 004 60.77% 99.66% 0.34% 0.40% number 4.1: Appointment of Bharti Harie as a member of the audit and risk committee Ordinary resolution 379 416 004 60.77% 99.69% 0.31% 0.40% number 4.2: Appointment of Amaresh Chetty as a member of the audit and risk committee Ordinary resolution 335 358 356 53.71% 55.16% 44.84% 7.46% number 4.3: Appointment of Lawrence Mulaudazi as a member of the audit and risk committee Ordinary resolution 379 446 004 60.77% 80.03% 19.97% 0.40% number 4.4: Appointment of Karsten Wellner as a member of the audit and risk committee Ordinary resolution 380 102 025 60.88% 79.55% 20.45% 0.29% number 5: General but restricted authority to place unissued shares under the control of director, limited to 10% Ordinary resolution 318 085 233 50.94% 95.77% 4.23% 10.22% number 6: Endorsement of Ascendis Health Remuneration Policy Ordinary resolution 318 085 233 50.94% 96.25% 3.75% 10.22% number 7: Endorsement of Ascendis Health Remuneration Implementation Report Special resolution 318 617 077 51.03% 97.55% 2.45% 10.14% number 1: Approval of non-executive directors’ remuneration for FY23 Special resolution 379 975 880 60.86% 65.33% 34.67% 0.31% number 2: Approval of financial assistance in terms of section 44 of the Act Special resolution 379 975 880 60.86% 65.33% 34.67% 0.31% number 3: Approval of financial assistance in terms of section 45 of the Act Additional ordinary 379 732 763 60.82% 83.58% 16.42% 0.35% resolution number 8: Change to Board of Directors, appointment of Theunis de Bruyn Note: 1. As a percentage of the total number of shares in issue as at the date of the AGM (excluding treasury shares). 2. As a percentage of the total number of shares voted at the AGM. 3. The total number of shares in issue as at the date of the AGM was 632,469,959 ordinary shares of which 8,091,150 were treasury shares. Accordingly, the total votable shares were 624,378,809 ordinary shares. 4. No resolutions were added or amended at the AGM. Change to Board of Directors In accordance with paragraph 3.59 of the Listings Requirements of the JSE Limited, shareholders are hereby advised the Mr. Harry Smit is no longer an independent non-executive director of the Company or the chairman of the board of directors of the Company (“Board”), with effect from today, 30 November 2022. The Board thanks Mr. Harry Smit for his contributions to Ascendis Health during his tenure of service and wishes him well in his future endeavours. 30 November 2022 Johannesburg Sponsor Valeo Capital (Pty) Limited Date: 30-11-2022 05:15:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.