Dispensation on 60 day rule to dispatch circular Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis Health” or “the Company”) DISPENSATION ON 60 DAY RULE TO DISPATCH CIRCULAR Shareholders are referred to the announcement released on 1 February 2022, wherein shareholders were, inter alia, advised that Ascendis Health SA Holdings Proprietary Limited (“AHSA”), a wholly-owned subsidiary of Ascendis Health, had concluded an agreement in terms of which it would dispose of its direct and indirect interest in the entities through which the business known as “Pharma” operates (the “Pharma Business”) to Pharma-Q Holdings Proprietary Limited and Imperial Logistics Limited (the “Pharma-Q/Imperial Pharma Disposal”). Shareholders are further referred to the announcement released on 19 July 2022, wherein shareholders were advised that AHSA had concluded an agreement in terms of which it would dispose of the Pharma Business to Austell Pharmaceuticals Proprietary Limited in the event that shareholders do not approve the Pharma-Q/Imperial Pharma Disposal (the “Austell Pharma Disposal”). Ascendis Health has received informal approval from the JSE in respect of the category 1 transaction circular to Ascendis Health shareholders in respect of the Pharma-Q/Imperial Pharma Disposal and expects to issue the circular on or about 13 September 2022. To this end, the Company has received a further dispensation from compliance with paragraph 9.20(b) of the JSE Limited Listings Requirements in respect of the Pharma-Q/Imperial Pharma Disposal, such that a circular containing details of the Pharma-Q/Imperial Pharma Disposal and the Austell Pharma Disposal, as well as a notice of general meeting to obtain the approval of shareholders for the Pharma-Q/Imperial Pharma Disposal and the Austell Pharma Disposal must now be issued on or before 30 September 2022. 5 September 2022 Bryanston Sponsor Questco Corporate Advisory Proprietary Limited Date: 05-09-2022 11:00:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.