Notice of Annual General Meeting Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis Health” or “the Company”) NOTICE OF ANNUAL GENERAL MEETING Shareholders are referred to the revised notice of Annual General Meeting (“AGM”) and to the announcement published on SENS on 18 November 2021 in which it was confirmed that the AGM would be held on 20 December 2021 (“the Revised Notice”). Shareholders are also referred to the announcement published on SENS on 15 December 2021 in which it was announced that the AGM was to be postponed (“the Postponement”). Shareholders are now advised that an urgent court application was launched on Saturday, 18 December 2021 by a shareholder of the Company, Cambridge Investments Proprietary Limited, and heard yesterday in the Gauteng Division of the High Court of South Africa (“the Court”), in terms of which the Postponement was declared invalid by the Court and the Company directed to hold the AGM at 9am, SA time, today, Monday 20 December 2021, as previously scheduled in accordance with the Revised Notice. The salient dates and times pertaining to the AGM are contained in the Revised Notice and remain applicable to the AGM that will take place this morning at 9am. With regard to instructions regarding electronic participation, please note that the meeting will now be held via Microsoft Teams. A link has been shared with shareholders that have submitted their proxy forms or letters of representation in accordance with the Revised Notice by the deadline set out therein. Any other interested party wishing to attend the meeting may send a written request to proxy@computershare.co.za before 09:00 on Monday 20 December 2021. 20 December 2021 Bryanston Sponsor Questco Corporate Advisory Proprietary Limited Date: 20-12-2021 07:15:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.