Trading Statement Aspen Pharmacare Holdings Limited (Incorporated in the Republic of South Africa) (Registration number 1985/002935/06) Share code: APN & ISIN: ZAE000066692 ("Aspen") Trading Statement Aspen shareholders are hereby advised that normalised headline earnings per share (“NHEPS”) , headline earnings per share and earnings per share for the 6 months ended 31 December 2016 are expected to vary from those reported in the comparative period, ended 31 December 2015, within the following ranges: Measure Range Cents per share Cents per share in Notes the comparative period - 31 December 2015 NHEPS 3% to 8% 675.2 to 707.9 655.5 1 Headline earnings per 49% to 57% 624.0 to 657.5 418.8 2 share Earnings per share -13% to -17% 603.5 to 632.6 727.1 3 Notes: 1. NHEPS comprises headline earnings per share adjusted for specific non-trading items. NHEPS is the primary measure used by management to assess Aspen’s underlying financial performance. 2. The significant increase in headline earnings per share is attributable to the once-off negative effect in the comparative period arising from the devaluation of Aspen’s Venezuelan business. 3. The decline in earnings per share is due to the positive effect of significant capital profits realised in the comparative period arising from the disposal of non-core businesses and products. The financial results on which this trading announcement is based have not been reviewed or reported on by Aspen`s external auditors. Aspen`s interim results for the 6 months ended 31 December 2016 are scheduled to be published on SENS on 9 March 2017. Durban 1 March 2017 Sponsor: Investec Bank Limited Date: 01/03/2017 05:00:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.