Dealings in securities by an associate of a director Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) DEALINGS IN SECURITIES BY AN ASSOCIATE OF A DIRECTOR In terms of paragraphs 3.63 to 3.74 of the Listings Requirements of the JSE Limited, the following information, relating to dealings in securities by an associate of a director, is disclosed: Name of director: Gary Shayne (non-executive) Name of associate: Cambridge Investments (Pty) Limited (“Cambridge Investments”) Nature and extent of interest: Indirect beneficial – Gary Shayne is a beneficiary of The Lighthouse Trust which holds a controlling interest in Cambridge Investments Nature of transactions: Involuntary, system-generated, on market sale, as a result of a forced sale actioned by a financial institution due to the contract for difference being linked to the Ascendis share price Class of security: Contract for difference in respect of ordinary shares Written clearance obtained: Clearance to trade was not obtained as the trade was involuntary Date of transaction: 12 May 2022 Number of securities: 960,221 Price per security: R0.67 Value: R643 531.47 RESPONSIBILITY STATEMENT The board of directors of Ascendis (the “Board”) accepts responsibility for the information contained in this announcement as it pertains to Ascendis. To the best of the Board's knowledge and belief, the information contained in this announcement as it pertains to Ascendis is true and nothing has been omitted which is likely to affect the importance of such information. Bryanston 13 May 2022 Sponsor Questco Corporate Advisory Proprietary Limited Date: 13-05-2022 04:05:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.