No Change Statement and Notice of Annual General Meeting – 9 December 2021 ASPEN PHARMACARE HOLDINGS LIMITED (Incorporated in the Republic of South Africa) (“Aspen Holdings”) Registration number: 1985/002935/06 Share code: APN ISIN: ZAE000066692 LEI: 635400ZYSN1IRD5QWQ94 and its subsidiaries (collectively “Aspen” or “the Group”) NO CHANGE STATEMENT AND NOTICE OF ANNUAL GENERAL MEETING – 9 DECEMBER 2021 NO CHANGE STATEMENT Shareholders are advised that the audited annual financial statements of Aspen Holdings and the Group for the 2021 financial year are now available on our website, https://www.aspenpharma.com/investor-information/ and at the registered office of the Company. The annual financial statements contain no modifications to the Reviewed Provisional Group Financial Results that were published on 1 September 2021. Ernst & Young Incorporated completed their audit of the Company and Group annual financial statements on 4 October 2021. Their unqualified audit report is presented in the 2021 audited Group and Company annual financial statements and is available for inspection at the registered office of the Company. NOTICE OF THE ANNUAL GENERAL MEETING The annual general meeting will be held on Thursday, 9 December 2021 at 10:00 at Aspen’s head office (Aspen Place, 9 Rydall Vale Park, Douglas Saunders Drive, La Lucia Ridge in Durban), to transact the business as stated in the notice of the annual general meeting. The record date to participate and vote at the AGM will be Friday, 3 December 2021 and the last day to trade will be Tuesday, 30 November 2021. Aspen’s 2021 integrated report will be made available on our website at the end of October 2021, with a SENS announcement being released to notify shareholders in this regard. The notice and proxy of the annual general meeting will be posted to shareholders at this time, together with the summarised audited Group annual financial statements. Durban 4 October 2021 Sponsor Investec Bank Limited Date: 04-10-2021 05:44:00 Supplied by www.sharenet.co.za Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.