Dealings in securities by an associate of a director Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) Dealings in securities by an associate of a director In terms of paragraphs 3.63 to 3.74 of the Listings Requirements of the JSE Limited, the following information, relating to dealings in securities by an associate of a director, is disclosed: Name of director: Gary Shayne (non-executive) Name of associate: Gane Holdings Proprietary Limited (“Gane Holdings”) Nature and extent of interest: Indirect beneficial – through Gane Holdings, in which Gary Shayne holds an indirect controlling shareholding through the ultimate holding company, Coast2Coast Communications Limited (“C2C”) Nature of transactions: Involuntary sale, on market, as a result of a forced sale actioned by a financial institution due to the shares being linked to an equity finance transaction resulting in a margin call. C2C is a long-term shareholder of Ascendis and remains confident in the strategy of the Company. Class of shares: Ordinary shares Written clearance obtained: Clearance was obtained from the Chairman Trade 1: Date of transaction: 29 November 2018 Number of shares: 88,424 Price per share (low): R3.96 Price per share (high): R4.10 Volume weighted average price: R4.0067 Value: R354,288.44 Trade 2: Date of transaction: 30 November 2018 Number of shares: 115,566 Price per share (low): R3.74 Price per share (high): R3.85 Volume weighted average price: R3.7669 Value: R435 325.57 Trade 3: Date of transaction: 3 December 2018 Number of shares: 28,446 Price per share (low): R3.79 Price per share (high): R3.94 Volume weighted average price: R3.8040 Value: R108,208.58 Trade 4: Date of transaction: 4 December 2018 Number of shares: 19,033 Price per share (low): R3.75 Price per share (high): R3.86 Volume weighted average price: R3.7954 Value: R72,237.85 Nature and extent of interest: Indirect beneficial – through Gane Holdings, in which Gary Shayne holds an indirect controlling shareholding through the ultimate holding company, Coast2Coast Communications Limited (“C2C”) Nature of transactions: On 26 February 2016, Gane Holdings issued a convertible debenture and, in terms of its contractual obligation, is now transferring Ascendis shares in part settlement thereof (off- market) Class of shares: Ordinary shares Written clearance obtained: Clearance was obtained from the Chairman Date of transaction: 29 November 2018 Number of shares: 5,545,103 Price per share: R4.62 Value: R25,618,375.86 Bryanston 5 December 2018 Sponsor Questco Corporate Advisory Proprietary Limited Date: 05/12/2018 03:01:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.