Dealings in securities by an associate of directors Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) Dealings in securities by an associate of directors In terms of paragraphs 3.63 to 3.74 of the JSE Listings Requirements, the following information, relating to dealings in securities by associates of directors of the Company, is disclosed: Directors: Gary Shayne and Crispian Dillon Type of director: Both directors serve on the board of directors of the Company as non-executive directors Name of associate: Gane Holdings Proprietary Limited (“Gane Holdings”) in which Gary Shayne and Crispian Dillon jointly hold an indirect controlling shareholding through the ultimate holding company, Coast2Coast Communications Limited Dealing 1: Acquisition of shares by Gane Holdings Nature of transaction: Shareholders are referred to the announcement dated 19 November 2015 relating to the acquisition by Ascendis of 100% of Akacia Healthcare Holdings Proprietary Limited and the subsequent directors’ dealings announcement (also dated 19 November 2015) in terms of which Gane Holdings granted the disposing shareholders (“Akacia Vendors”) a put option, and the Akacia Vendors granted Gane Holdings a reciprocal call option, in respect of the Ascendis shares issued as part settlement of the purchase consideration (“Option Agreement”). Gane Holdings has now exercised its call option pursuant to the Option Agreement and purchased a pre-determined number of Ascendis shares from the Akacia Vendors. Date of transaction: 7 May 2018 Type of transaction: Off-market purchase of shares Class of shares: Ordinary shares Number of shares purchased in terms of the call option exercised: 2,569,282 Option exercise price: R33.4198 Total value of the transaction: R85,864,983.35 Nature of interest: Indirect beneficial Written clearance obtained: Clearance was obtained from the Chairman Dealing 2: Sale of shares by Gane Holdings Nature of transaction: Sale of Ascendis shares by Gane Holdings in settlement of a pre-agreed financing arrangement entered into by Gane Holdings and an external financier Date of transaction: 9 May 2018 Type of transaction: Off-market sale of shares Class of shares: Ordinary shares Number of shares: 5,870,841 Price per share: R24.9088 Total value of transaction: R146,235,604.30 Nature of interest: Indirect beneficial Written clearance obtained: Clearance was obtained from the Chairman Bryanston 10 May 2018 Sponsor Questco Corporate Advisory Proprietary Limited Date: 10/05/2018 05:15:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.