Trading statement ASCENDIS HEALTH LIMITED (Incorporated in the Republic of South Africa) (Registration number 2008/005856/06) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) TRADING STATEMENT In terms of paragraph 3.4(b) of the JSE Limited’s Listings Requirements, Ascendis shareholders are hereby advised that the Company’s financial results for the twelve months ended 30 June 2017 are expected to be more than 20% higher than the previous corresponding period. The table below illustrates the ranges anticipated against the comparative period: Continuing Operations 12 months 12 months % increase/ ended ended (decrease) 30 June 2017 30 June 2016 reported Normalised headline earnings R612m – R652m R336m 82% – 94% Normalised headline earnings per share 148 – 159 cents 121 cents 22% – 31% (“NHEPS”) Basic earnings R342m – R367m R159m 115% – 131% Basic earnings per share (“EPS”) 83 – 89 cents 57 cents 45% – 56% Headline earnings R353m – R383m R154m 129% - 149% Headline earnings per share (“HEPS”) 86 – 93 cents 56 cents 54% - 66% Total Operations 12 months 12 months % increase/ ended ended (decrease) 30 June 2017 30 June 2016 Normalised headline earnings R571m – R612m R336m 70% – 82% Normalised headline earnings per share 138 – 148 cents 121 cents 14% – 22% (“NHEPS”) Basic earnings R270m – R296m R159m 70% – 86% Basic earnings per share (“EPS”) 65 – 72 cents 57 cents 14% – 26% Headline earnings R310m – R340m R154m 101% - 121% Headline earnings per share (“HEPS”) 75 – 82 cents 56 cents 34% - 46% Notes: 1. During the year under review one of the Company’s manufacturing plants met the requirements for classification as a discontinued operation in terms of International Financial Reporting Standards (IFRS). This relates to a project to consolidate manufacturing operations in South Africa to improve efficiency going forward. NHEPS, EPS and HEPS in respect of the comparative period ended 30 June 2016 for “Continuing Operations” have been restated accordingly. 2. Normalised headline earnings comprise basic earnings adjusted for specific non-trading items and once-off costs. Once-off costs amounted to c.R175m and comprised predominantly of transaction and financing costs related to the acquisitions of Remedica, Scitec, Sunwave and Cipla concluded within the current financial period. 3. The Remedica and Scitec acquisitions concluded in August 2016 (as per SENS announcement dated 26 August 2016) have only been consolidated for 11 months whilst the Sunwave and Cipla acquisitions concluded on 1 June 2017 (as per SENS announcements dated 6 March 2017 and 7 March 2017 respectively) have therefore only been consolidated for 1 month of the financial period. Post conclusion of the international acquisitions, Ascendis’ non-South African earnings account for c.60% of its total earnings on a consolidated basis. 4. Other than the shares issued and disclosed in the interim financial results for the six months ended 31 December 2016, no further shares were issued in the current financial period. Despite a challenging trading environment, Ascendis is pleased with the overall resilient performance of its diversified business model during the current financial period. The financial information on which this trading statement is based has not been reviewed or reported on by the Company’s auditors. Shareholders are advised that the results for the twelve months ended 30 June 2017 are scheduled to be released on SENS on 12 September 2017, to be presented in Cape Town on 13 September 2017 and in Johannesburg on 14 September 2017. 24 August 2017 Johannesburg Sponsor Investec Bank Limited Date: 24/08/2017 03:20:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.