Dealings in securities by directors ASCENDIS HEALTH LIMITED (Incorporated in the Republic of South Africa) (Registration number 2008/005856/06) ISIN: ZAE000185005 Share code: ASC (“Ascendis”) Dealings in securities by directors In terms of paragraphs 3.63 to 3.74 of the JSE Listings Requirements, the following information, relating to dealings in securities by directors, is disclosed: Directors: Gary Shayne and Crispian Dillon. Nature of the transaction: Coast2Coast Capital Proprietary Limited (“C2C”) (in which Gary Shayne holds an 85% indirect interest and Crispian Dillon holds a 15% indirect interest), is required to redeem two existing debentures issued in 2014 by an indirect subsidiary of C2C by way of a settlement of Ascendis shares. The Ascendis shares are thus transferred to effect the redemption of the debentures at pre-determined discounts to the 30 day volume weighted average prices on 2 December 2016 and 5 December 2016, being R25.15 and R25.00 respectively. The discounts were applied to achieve an agreed return on the debentures and therefore should not be used to evaluate a fair share price for Ascendis in the open market. Debenture 1: Number of shares: 456,103 Price per share: R21.925 Value: R10,000,058 Date of transaction: 15 December 2016 Class of shares: Ordinary shares Nature of transaction: Sale, off market Extent of interest: Indirect beneficial (through C2C, in which Gary Shayne has a 85% indirect beneficial interest and Crispian Dillon has a 15% indirect beneficial interest). Written clearance obtained: Clearance was obtained from the Chairman. Debenture 2: Number of shares: 883,588 Price per share: R22.635 Value: R20,000,014 Date of transaction: 15 December 2016 Class of shares: Ordinary shares Nature of transaction: Sale, off market Extent of interest: Indirect beneficial (through C2C, in which Gary Shayne has a 85% indirect beneficial interest and Crispian Dillon has a 15% indirect beneficial interest). Written clearance obtained: Clearance was obtained from the Chairman. 19 December 2016 Johannesburg Sponsor Investec Bank Limited Date: 19/12/2016 05:00:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.