Dealings in securities by directors ASCENDIS HEALTH LIMITED (Incorporated in the Republic of South Africa) (Registration number 2008/005856/06) ISIN: ZAE000185005 Share code: ASC (“Ascendis”) Dealings in securities by directors In terms of paragraphs 3.63 to 3.74 of the JSE Listings Requirements, the following information, relating to dealings in securities by directors, is disclosed: Directors: Gary Shayne and Crispian Dillon. Nature of the transaction: Coast2Coast Capital Proprietary Limited (“C2C”) (in which Gary Shayne holds an 85% indirect interest and Crispian Dillon holds a 15% indirect interest), is required to redeem an existing debenture issued by an indirect subsidiary of C2C by way of a settlement of Ascendis shares. The Ascendis shares are thus transferred to effect the redemption of the debenture at a pre-determined discount to the 30 day volume weighted average price at 1 July 2016 of R23.78. The discount was applied to achieve an agreed return on the debenture and therefore should not be used to evaluate a fair share price for Ascendis in the open market. Number of shares: 1,401,975 Price per share: R21.3984 Value: R30,000,000 Date of transaction: 27 October 2016 Class of shares: Ordinary shares Nature of transaction: Sale, off market Extent of interest: Indirect beneficial (through C2C, in which Gary Shayne has an 85% indirect beneficial interest and Crispian Dillon has a 15% indirect beneficial interest). Written clearance obtained: Clearance was obtained from the Chairman. 1 November 2016 Johannesburg Sponsor Investec Bank Limited Date: 01/11/2016 08:30:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.