Trading Statement ASCENDIS HEALTH LIMITED (Incorporated in the Republic of South Africa) (Registration number 2008/005856/06) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) TRADING STATEMENT In terms of paragraph 3.4(b) of the JSE Limited’s Listings Requirements, Ascendis shareholders are hereby advised that the Company’s financial results for the six months ended 31 December 2015 are expected to be more than 20% higher than the previous corresponding period. The table below illustrates the ranges anticipated against the comparative period: 6 months ended 6 months ended 31 December 31 December % increase 2015 2014 Normalised Headline Earnings R146m – R154m R107m 36% – 44% Normalised Headline Earnings per share 54 – 57 cents 43 cents 26% – 33% Basic Earnings/Headline Earnings R124m – R133m R89m 39% – 49% Basic Earnings/Headline Earnings per share 46 – 49 cents 35 cents 31% – 40% Profit after tax (note #4) R128m – R134m R89m 44% – 51% Notes: 1. Normalised headline earnings comprise basic earnings adjusted for specific non-trading items and once-off costs. 2. NHEPS comprises normalised headline earnings per share adjusted for specific non-trading items and once off costs. 3. The “per share” measures reflect a lower percentage increase than the earnings numbers due to the change in weighted average number of shares of c.21m being an increase of 8%, due to additional shares issued by Ascendis during the course of the six month period. 4. The profit after tax is exclusive of minority shareholders’ interests. The financial information on which this trading statement is based has not been reviewed or reported on by the Company’s auditors. Shareholders are advised that the results for the six months ended 31 December 2015 are scheduled to be released on SENS on 9 March 2016 and to be presented in Cape Town on the 9th of March 2016 and Johannesburg on the 10th of March 2016. 2 March 2016 Johannesburg Sponsor Investec Bank Limited Date: 02/03/2016 07:30:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.