Trading Statement ASCENDIS HEALTH LIMITED (Incorporated in the Republic of South Africa) (Registration number 2008/005856/06) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) TRADING STATEMENT In terms of paragraph 3.4(b) of the JSE Limited’s Listings Requirements, Ascendis shareholders are hereby advised that the Company’s financial results for the twelve months ended 30 June 2015 are expected to be more than 20% higher than the previous corresponding period. The table below illustrates the ranges anticipated against the comparative period: year ended year ended % increase 30 June 2015 30 June 2014 Normalised Headline Earnings R237m – R248m R153m 55% – 62% Normalised Headline Earnings per share 90 – 95 cents 72 cents 25% – 32% Basic Earnings/Headline Earnings R201m – R211m R136m 48% – 55% Basic Earnings/Headline earnings per 78 – 81 cents 64 cents 22% – 27% share Operating profit R353m – R368m R214m 65% – 72% Notes: 1. Normalised earnings comprise basic earnings adjusted for specific non- trading items and once-off costs. 2. NHEPS comprises normalised headline earnings per share adjusted for specific non-trading items and once off costs. 3. The “per share” measures reflect a lower percentage increase than the earnings numbers due to the change in weighted average number of shares of c.48m being an increase of 23%, due to additional shares issued by Ascendis during the course of the year. The financial information on which this trading statement is based has not been reviewed or reported on by the Company’s auditors. Shareholders are advised that the results for the twelve months ended 30 June 2015 are scheduled to be released on SENS on 9 September 2015 and to be presented in Cape Town on the 9th and Johannesburg on the 10th of September 2015. 1 September 2015 Johannesburg Sponsor Investec Bank Limited Date: 01/09/2015 02:20:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.