Dealings in securities by directors and notification in terms of Section 122(3) ASCENDIS HEALTH LIMITED (Incorporated in the Republic of South Africa) (Registration number 2008/005856/06) ISIN: ZAE000185005 Share code: ASC (“Ascendis”) Dealings in securities by directors and notification in terms of Section 122(3) of the Companies Act and Section 3.83(b) of the JSE Listings Requirements In terms of paragraphs 3.63 to 3.74 of the JSE Listings Requirements, the following information, relating to dealings in securities by directors, is disclosed: Directors: Gary Shayne and Crispian Dillon. Nature of the transaction: Further to the announcement released on 26 June 2014 (the “Announcement”) referring to the agreement entered into between Gane Holdings Proprietary Limited (“Gane Holdings”) and MIC Investment Holdings Proporietary Limited (“MIC”) (the “Agreement”), Ascendis shareholders are hereby advised of the settlement of the first tranche of the R200 million convertible debentures as at 14 August 2015 by way of a pre-determined transfer of Ascendis ordinary shares at a pre-determined discount to the prevailing share price, and as such the directors do not exercise discretion in the timing of this transaction. The discount was only applied to achieve an agreed return for the debenture and therefore should not be used to evaluate a fair share price for Ascendis in the open market. No fees are payable by Ascendis to Gane Holdings relating to the implementation of this Agreement. Gane Holdings is a 100% held subsidary of Coast2Coast Investments Proprietary Limited in which Gary Shayne holds an 85% indirect interest and Crispian Dillon holds a 15% indirect interest. Number of shares: 2,265,314 Price per share: R13.24 Value: R30,000,000.00 Date of transaction: 14 August 2015 Class of shares: Ordinary shares Nature of transaction: Sale, off market Extent of interest: Indirect beneficial (through Gane Holdings, in which Gary Shayne has a 85% indirect beneficial interest and Crispian Dillon has a 15% indirect beneficial interest). Written clearance obtained: Clearance was obtained from the Chairman. Further to the above listed dealings in securities by directors and in accordance with section 122(3)(b) of the Companies Act, No. 71 of 2008 (“the Act”), and section 3.83(b) of the JSE Listings Requirements, holders of ordinary shares in the Company are advised that Coast2Coast Holdings Proprietary Limited Group’s (“Coast2Coast”) beneficial interests in the Company now amounts to 44.82% of the total number of shares in issue (from 45.66% of the total number of shares in issue prior to this dealing). Ascendis hereby confirms that it has received the required notice from Coast2Coast in terms of section 122(1)(a) of the Act. As required in terms of section 122(3)(a) of the Act, Ascendis will file the required notice with the Takeover Regulation Panel. 14 August 2015 Johannesburg Sponsor Investec Bank Limited Date: 14/08/2015 04:35:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.