Announcement regarding the acquisition of a material interest in the company and renewal of cautionary Adcock Ingram Holdings Limited (Incorporated in the Republic of South Africa) Registration number 2007/016236/06 Share code: AIP ISIN: ZAE000123436 (“Adcock Ingram” or “the Company”) ANNOUNCEMENT REGARDING THE ACQUISITION OF A MATERIAL INTEREST IN THE COMPANY AND RENEWAL OF CAUTIONARY Adcock Ingram shareholders are referred to the announcement released on SENS by The Bidvest Group Limited (“Bidvest”) at approximately 10h15 this morning. The independent board of Adcock Ingram (“the Independent Board”) wishes to advise shareholders that approximately 39 million Adcock Ingram ordinary shares equating to approximately 22% of the issued ordinary share capital of the Company (excluding the A and B ordinary shares and the treasury shares) (“Adcock Ingram Ordinary Shares”) traded on 30 January 2014. Shareholders will be aware that the Public Investment Corporation (“PIC”) and Bidvest, who held more than 25% of the Adcock Ingram Ordinary Shares in aggregate prior to yesterday, have each publicly expressed their opposition to the scheme of arrangement proposed between Adcock Ingram and the holders of Adcock Ingram Ordinary Shares regarding the offer from CFR Pharmaceuticals S.A. (“CFR”) (“the Scheme”) to be voted on at the Combined General Meeting and the Ordinary General Meeting (“the General Meetings”), adjourned in December 2013. Since the General Meetings were adjourned, the Independent Board is aware that CFR has been attempting to engage with the PIC to address its concerns in relation to the Scheme. It has now been confirmed to Adcock Ingram that most of the approximately 39 million Adcock Ingram Ordinary Shares that traded on 30 January 2014 were acquired by the consortium comprising Bidvest and Community Investment Holdings Proprietary Limited (“the Bidvest Consortium”). As a consequence, the Bidvest Consortium, which now holds approximately 32% of the Adcock Ingram Ordinary Shares, is in a position to unilaterally block the approval of the Scheme. In the circumstances, the Independent Board cannot envisage a realistic basis on which the Scheme will be approved. However, unless and until otherwise agreed between the Company and CFR (and subject also to any regulatory approvals that may be required) the Company and CFR remain bound in terms of the Transaction Implementation Agreement (as amended) (“TIA”) entered into between them on 11 September 2013 to proceed with the proposal of the Scheme to Adcock Ingram Ordinary Shareholders at the adjourned General Meetings. The Independent Board will be urgently engaging with CFR regarding the implications of these developments for both the Scheme and the TIA. Shareholders are accordingly advised to continue exercising caution when dealing in the Company’s securities until a further announcement is made. For media enquiries: Brunswick Tel: +27 11 502 7300 Carol Roos +27 72 690 1230 Marina Bidoli +27 83 253 0478 Midrand 31 January 2014 Financial Adviser and Sponsor to Adcock Ingram Deutsche Bank Legal Adviser to Adcock Ingram in South Africa Read Hope Phillips Attorneys Public Relations Adviser to Adcock Ingram Brunswick Date: 31/01/2014 12:45:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.