Directors dealings ASPEN PHARMACARE HOLDINGS LIMITED (Incorporated in the Republic of South Africa) Registration number 1985/0002935/06 Share code: APN ISIN: ZAE000066692 ("Aspen" or "the Company") DEALING IN SECURITIES BY DIRECTORS OF A MAJOR SUBSIDIARY In compliance with paragraph 3.63 of the Listings Requirements of the JSE Limited, disclosure is made of the following information: Director : Gregory Lan Subsidiary Company : Aspen Asia Pacific Pty Limited Date of transaction : 3 October 2012 Nature of transaction : Acceptance of share appreciation rights Number of securities : 30 239 Class of securities : Ordinary shares Grant price : R142.20 Value of Transaction : R 4 300 000.00 Nature of interest : Direct beneficial Clearance obtained : Yes Director : Trevor Ziman Subsidiary Company : Aspen Asia Pacific Pty Limited Date of transaction : 3 October 2012 Nature of transaction : Acceptance of share appreciation rights Number of securities : 30 239 Class of securities : Ordinary shares Grant price : R142.20 Value of Transaction : R 4 300 000.00 Nature of interest : Direct beneficial Clearance obtained : Yes All acceptances of share appreciation rights are deemed to be off- market trades. Durban 5 October 2012 Sponsor Investec Bank Limited Date: 05/10/2012 07:06:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.